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Clinical Trials/NCT05792098
NCT05792098
Enrolling By Invitation
Not Applicable

Percutaneous Dilatational Tracheostomy and Thyroid Isthmus Penetration

Charles University, Czech Republic1 site in 1 country200 target enrollmentApril 6, 2023

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Tracheostomy Complication
Sponsor
Charles University, Czech Republic
Enrollment
200
Locations
1
Primary Endpoint
The guidewire penetration through the thyroid isthmus.
Status
Enrolling By Invitation
Last Updated
3 years ago

Overview

Brief Summary

A prospective randomized interventional study will be conducted in the Military University Hospital Prague at the department of Anesthesiology and Intensive care. The incidence of thyroid isthmus penetration will be evaluated during percutaneous dilatational tracheostomy in two groups (ultrasound-guided puncture vs. standard approach using only anatomical landmarks).

Detailed Description

A prospective randomized interventional study will be conducted in the Military University Hospital Prague at the department of Anesthesiology and Intensive care. Patients indicated by the attending physician to percutaneous dilatational tracheostomy (PDTS) due to long-term need for mechanical ventilation will be randomly divided into two groups. The standard procedure group will undergo PDTS by the attending physician in the standard manner based on clinical examination and anatomical landmarks using bronchoscopic navigation. In the second group, the attending physician will additionally use ultrasound navigation during the procedure. After insertion of the guidewire, before dilation is performed, patients in both groups will be examined by ultrasound by an independent physician - the study investigator - who will verify the position of the guidewire and its relationship to the surrounding structures. In case of malposition of the guidewire (unacceptable lateral or craniocaudal), the penetration site will be adjusted and the PDTS completed.

Registry
clinicaltrials.gov
Start Date
April 6, 2023
End Date
December 12, 2025
Last Updated
3 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Sponsor
Charles University, Czech Republic
Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • 18 Years and older
  • long-term need for mechanical ventilation

Exclusion Criteria

  • not willing to participate

Outcomes

Primary Outcomes

The guidewire penetration through the thyroid isthmus.

Time Frame: During procedure

Incidence of guidewire penetration through the thyroid isthmus in standard and ultrasound navigated percutaneous dilatational tracheostomy.

Monitoring the incidence of early postoperative complications.

Time Frame: Up to 10 days

The incidence of bleeding from tracheostomy canal during hospitalization depending on guidewire position, defined as the need for any intervention to stop the bleeding. The incidence of tracheostomy canal infection during hospitalization depending on guidewire position, defined as the presence of any clinical signs of inflammation (swelling, redness, pain, secretion production, dehiscence).

Secondary Outcomes

  • Using ultrasound examination as a tool for PDTS navigation in terms of correct puncture site.(During procedure)

Study Sites (1)

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