Thyroidectomy Improves Tracheal Anatomy and Airflow in Patients With Nodular Goiter: A Prospective Cohort Study
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Goiter, Nodular
- Sponsor
- University of Southern Denmark
- Enrollment
- 72
- Primary Endpoint
- Changes in tracheal anatomy
- Status
- Completed
- Last Updated
- 9 years ago
Overview
Brief Summary
The investigators aimed at investigating the effects of thyroidectomy on tracheal anatomy and airflow in patients with benign nodular goiter, employing a prospective observational study.
Magnetic resonance images of the neck and respiratory flow-volume curves were performed prior to and six months following surgery. Tracheal and thyroid volumes, smallest cross-sectional area of the trachea (SCAT), tracheal narrowing, tracheal deviation and tracheal encirclement by the thyroid were evaluated. Through flow-volume curves respiratory function, including both in- and expiration, was evaluated.
Investigators
Jesper Roed Sorensen
PhD Fellow
University of Southern Denmark
Eligibility Criteria
Inclusion Criteria
- •Reads and write Danish
Exclusion Criteria
- •Suspected or present malignancy
- •Neuromuscular disease
- •Prior surgery to the neck
Outcomes
Primary Outcomes
Changes in tracheal anatomy
Time Frame: 6 months follow-up
Change in tracheal narrowing (cross sectional area of the trachea at the goiter level compared to cross-sectional area of the trachea at the carina)