Treatment Outcomes and Predictive Factors of the Effectiveness and Adherence of Moodpep: an Online Self-help Intervention for College Students With Depressive Symptoms

Not Applicable

Completed

• Conditions: Internet-based Intervention; Depression; Adherence; Predictors; Students; Effectiveness

• Registration Number: NCT07030244
• Lead Sponsor: Universiteit Leiden

Brief Summary

Depressive symptoms are prevalent among college students and often remain untreated. E-health interventions may help overcome treatment barriers by offering accessible and flexible support. This study will evaluate the effects of Moodpep, a guided online intervention for college students with depressive symptoms, and will examine predictors of treatment success and adherence.

Detailed Description

Not available

Study Timeline

• Study Start: 2020-06-01
• Primary Completion: 2024-05-31
• Study Completion: 2024-05-31
• Status Verified: 2025-06
• Study First Submitted: 2025-06-12
• Study First Submitted QC: 2025-06-12
• Study First Posted: 2025-06-22
• Last Update Submitted: 2025-06-23
• Last Update Posted: 2025-06-27

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 1050

Inclusion Criteria

Not provided

Exclusion Criteria

Not provided

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Primary Outcome Measures

Name	Time	Method
Depressive symptoms (PHQ-9)	T0 (baseline), T1 (6 weeks post-baseline), T2 (6 months post-baseline)	Patient Health Questionnaire-9 (PHQ-9; Kroenke et al., 2001). Total scores range from 0 to 27 with higher scores indicating more depressive symptoms.

Secondary Outcome Measures

Name	Time	Method
Adherence	T1 (6 weeks post-baseline)	Number of modules completed (1-8). For the logistic regression analysis, 2 categories will be made: participants who completed 1 module and participants who completed 2-8 modules.
Predictors	T0 (baseline)	Age, gender (male, female), nationality (Dutch, international), current psychotropic medication use (yes, no), and current psychotherapy (yes, no).

Trial Locations

Locations (2)

VU Amsterdam; 🇳🇱 Amsterdam, Netherlands

Leiden University; 🇳🇱 Leiden, Netherlands