Determination of time and amount of hyper tonic saline required to induce a 15% FEV1 decrease in asthmatic patients referred to shahid beheshti hospita,l Kasha
Phase 2
- Conditions
- Asthma.Mixed asthma
- Registration Number
- IRCT201104266187N2
- Lead Sponsor
- Kashan University of Medicine Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 50
Inclusion Criteria
asthmatic patients, age between 15 to 60 with FEV1>60%
Exclusion criteria: pneumonia; bronchectasia, advance interstitial lung disease; pulmonary fibrosis; chronic obstructive pulmonary disease and valvular & congenital heart disease.
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 15% decrease in FEV1. Timepoint: 0.5 minute. Method of measurement: Spirometry.;15%decrease in FEV1. Timepoint: 1 minute. Method of measurement: spirometry.;15% decrease in FEV1. Timepoint: 2 minute. Method of measurement: spirometry.;15% decrease in FEV1. Timepoint: 4 minute. Method of measurement: spirometry.;15% decrease in FEV1. Timepoint: 6 minute. Method of measurement: spirometry.;15% decrease in FEV1. Timepoint: 8 minute. Method of measurement: spirometry.
- Secondary Outcome Measures
Name Time Method 20% decrease in PEF. Timepoint: 0.5 minute. Method of measurement: spirometry.;20% decrease in PEF. Timepoint: 1 minute. Method of measurement: spirometry.;20% decrease in PEF. Timepoint: 2 minute. Method of measurement: spirometry.;20% decrease in PEF. Timepoint: 4 minute. Method of measurement: spirometry.;20% decrease in PEF. Timepoint: 6 minute. Method of measurement: spirometry.;20% decrease in PEF. Timepoint: 8 minute. Method of measurement: spirometry.