Influence of magnesium-rich mineral waters on parameters of glucose metabolism in type 2 diabetes mellitus
Not Applicable
- Conditions
- E11Type 2 diabetes mellitus
- Registration Number
- DRKS00029256
- Lead Sponsor
- Gottfried Wilhelm-Leibniz-Universität Hannover Institut für Lebensmittelwissenschaft und Humanernährung
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting stopped after recruiting started
- Sex
- All
- Target Recruitment
- 23
Inclusion Criteria
Diabetes type 2 diagnosis; BMI between 20 and 35;
Willingness to consume 2-2.5 liters of mineral water daily for 12 weeks.
Exclusion Criteria
Insulin therapy; recent (<2 months) change in medications or supplements affecting blood glucose; diagnosed blood coagulation disorders as well as taking anticoagulant medications such as Marcumar (except ASA); participation in another clinical trial within the last 30 days
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method HbA1c levels after 12 weeks of intervention.
- Secondary Outcome Measures
Name Time Method Except for size, all parameters are recorded at baseline and after 12 weeks. <br><br>Blood: <br>Fasting glucose,<br>Fasting insulin,<br>HOMA index,<br>Inflammatory parameters (C-Peptide/hsCRP), <br>Magnesium,<br>Calcium,<br>25-Vitamin D,<br>TG, LDL, HDL, Total cholesterol,<br>Blood count (in particular Neutrophil-Lymphocyte ratio and Platelet-Lymphocyte ratio),<br>Safety parameters (creatinine, GOT, GPT, GGT);<br><br>Urine:<br>Magnesium,<br>Calcium,<br>Kalium,<br>Creatinine,<br>Uric acid;<br><br>Questionnaires:<br>3-day food record, <br>Short Form of Health (SF-36),<br>Single-item sleep quality scale (SQS),<br><br>Other parameters:<br>Blood pressure, pulse,<br>Anthropometric measures: weight, height, BMI, waist circumference,<br>Arterial stiffness via carotid-femoral pulse wave velocity,<br>