Empyema in Children.To obtain an accurate assessment of the disease burden among children with parapneumonic effusions and empyema associated with S.pneumoniae. There is potential to affect the national vaccination program if the project highlights that there is a large proportion of types of Streptococcus causing disease in children not covered by the current vaccine.

Not Applicable

Completed

• Conditions: Empyema; Streptococcus pneumoniae; Infection - Studies of infection and infectious agents; Respiratory - Other respiratory disorders / diseases

• Registration Number: ACTRN12607000476437
• Lead Sponsor: A/Prof Adam Jaffe (Principle Investigator)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2007-09-21
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 200

Inclusion Criteria

Children whose clinical condition necessitates drainage of pleural fluid secondary to pneumonia, and who present with the classical features of empyema; fever, cough, raised white cell count, raised C-reactive protein (CRP) and fluid present on ultrasound.

Exclusion Criteria

Those over the age of 16yrs old, and those who do not present to a paediatric hospital

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Identify the bacterial causes of empyema, including description and distribution of strains causing pneumococcal empyema[At the completion of the observational study (24 months)]

Secondary Outcome Measures

Name	Time	Method
To determine incidence and prevelance of empyema, describing epidemiology, clinical features and current management[At the completion of the observational study (24 months)]