Role of Sphingolipids in Pulmonary Edema

Completed

• Conditions: Pulmonary Edema

• Registration Number: NCT01162161
• Lead Sponsor: RWTH Aachen University

Brief Summary

In this mono-center prospective study, the impact of changes in the sphingolipid metabolism in patients with pulmonary edema will be investigated.

Detailed Description

There will be three groups of patients:

1. hydrostatic pulmonary edema

2. toxic pulmonary edema

3. not ventilated patients without any pulmonary edema

Samples of a routine bronchoalveolar lavage and EDTA-blood will be analysed in respect of sphingolipids, ceramide, sphingomyelin-phosphodiesterase and several cytokines.

Study Timeline

• Study Start: 2010-07
• Study First Submitted: 2010-07-13
• Study First Submitted QC: 2010-07-13
• Study First Posted: 2010-07-14
• Primary Completion: 2012-12
• Study Completion: 2013-05
• Status Verified: 2015-09
• Last Update Submitted: 2015-09-22
• Last Update Posted: 2015-09-23

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 45

Inclusion Criteria

• above the age of 18

Exclusion Criteria

• taking steroids

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Trial Locations

Locations (1)

Medical Clinic I, University Hospital Aachen; 🇩🇪 Aachen, Nordrhein-Westfalen, Germany