Protocol of PEEP Decrement Guided by Lung Volume Changes Shortens Time to Spontaneous Breathing Trial in Recovering ARDS Patients: A Randomized Controlled Trial

Phase 3

Recruiting

• Conditions: Patients with recovering ARDS who are assisted with mechanical ventilation; Protocol; Lung volume change; PEEP Decrement; Time to Spontaneous Breathing Trial; Recovering ARDS

• Registration Number: TCTR20200206001
• Lead Sponsor: one

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2020-02-06
• Study Completion: 2022-12-01
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 68

Inclusion Criteria

Patients with recovering ARDS who are assisted with mechanical ventilation
patients with PF ratio > 150
patients assisted with PEEP at least 8 cmH2O
patients assisted with FiO2 equal or less than 60% to keep SpO2 >90%
patients with stable condition and stable FiO2 > 24 hours

Exclusion Criteria

Age < 18 years old
Pneumothorax, Hemothorax, recent thoracic surgery
Active heart disease
COPD or lung bleb
pregnancy

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
time to SBT during study period number

Secondary Outcome Measures

Name	Time	Method
ung Collapse events during study period number,Lung collapse predictors during study period number