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Anisometropia Amblyopia Improved by Perceptual Learning and Patching

Phase 3
Completed
Conditions
Anisometropic Amblypia
Registration Number
NCT00498641
Lead Sponsor
Tri-Service General Hospital
Brief Summary

To compare the effects of perceptual learning with patching on improving visual acuity and contrast sensitivity in payient with anisometropic amblyopia.

Detailed Description

Patients with anisometropic amblyopia were randomized to patching or perceptual learning group. Corrected amblyopic logMAR visual acuity and contrast sensitivity function were measured at four-weekly intervals until visual acuity stabilized or amblyopia resolved. Improvement in visual acuity, contrast sensitivity, and the resolution of amblyopia were compared between groups.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
Not specified
Inclusion Criteria
  • Anisometropia without strabismus
  • An interocular acuity difference of at least 0.2 logMAR in children (3-7 years of age) or in older children and adult patients without a history of patching or atropine penalization
  • All patients wore their spectacle at least one year
Exclusion Criteria
  • A history of prior spectacle correction
  • A history of patching or optical penalization
  • The existence of an ocular disease that could contribute to decreased visual acuity
  • Learning difficulties
  • The presence of strabismus

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Primary Outcome Measures
NameTimeMethod
Corrected amblyopic logMAR visual acuity and contrast sensitivity function
Secondary Outcome Measures
NameTimeMethod
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