Perceptual learning in enhanced amblyopia treatment
- Conditions
- AmblyopiaEye Diseases
- Registration Number
- ISRCTN14022536
- Lead Sponsor
- HS Greater Glasgow and Clyde (UK)
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 60
1. Age 5 to 17 years
2. Visual acuity of 0.2 log units or lower in worst eye and/or interocular difference of at least 0.1 log units
3. Presence of anisometropia >1.00 MSE and/or strabismus/microtropia.
4. Not receiving any active conventional amblyopia treatment
5. Participants will all have a refraction, fundus and media check within 6 months prior to enrolment and will wear their up-to-date refractive correction for testing and training. It is important to establish that full spectacle adaptation has occurred.
1. Stimulus deprivation amblyopia
2. Presence of other known ophthalmic defect (bar refractive error)
3. Receiving active conventional amblyopia treatment
4. Cortical visual impairment
5. Photosensitive epilepsy
6. Physical impairment affecting ability to use mouse/keyboard
7. Previous perceptual learning treatment
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Proportion of patients with visual acuity improvement of 0.1 log units or better in the amblyopic eye at the end of the training period
- Secondary Outcome Measures
Name Time Method 1. Sensory fusion status (assessed with Bagolini glasses) <br>2. Motor fusion reserves (measured using horizontal prism bar)<br>3. Stereoacuity (measured using Frisby and/or Preschool Randot Stereotest)<br>4. Interocular suppression density (measured using Sbisa bar)<br>5. Angle of strabismus (measured using prism cover test) <br>6. Severity of perceptual visual distortions (measured using a 5 minute computer game that has been extensively piloted with amblyopic and visually normal children)<br><br>These are measured at the end of training.