Cardiovascular autonomic function in chronic obstructive pulmonary disease

• Conditions: Cardiovascular autonomic function in chronic obstructive pulmonary disease (COPD) patients with all stages; COPD, cardiovascular autonomic function

• Registration Number: TCTR20220519004
• Lead Sponsor: Faculty of Medicine Siriraj Hospital, Mahidol University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2022-05-19
• Study Completion: 2023-05-19
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: nknown
• Sex: All
• Target Recruitment: 88

Inclusion Criteria

COPD patients, all severity (mild, moderate, severe and very severe), as defined by the Global Initiative for Obstructive Lung Disease (GOLD) guidelines (2) with forced expiratory volume in 1 second (FEV1)/forced vital capacity (FVC) ratio < 0.7 will be recruited if they meet the following criteria:
1) Age between 40-80 years old;
2) Stable conditions, i.e. no acute exacerbation, change in pharmacological therapy, or hospital admission in the past 1 month;
3) Good ability to communicate and follow instructions.

Exclusion Criteria

Subjects of either group will be excluded from this study if they meet the following criteria:
1) History of diabetes mellitus, cardiac arrhythmias, lung cancer, or mental disorder;
2) Alcoholism and/or current smoker;
3) Musculoskeletal or neurological abnormalities, such as stroke, upper limb or lower limb injuries;
4) Acute conditions, such as fever, uncontrolled hypertension.

Study & Design

• Study Type: Observational
• Study Design: Not specified