Administration of clinical doses of neostigmine, commonly used in anaesthesia, and assessment of its effects on muscle strength, using a dynamometer, in healthy awake volunteers.

Phase 4

Completed

• Conditions: eostigmine induced muscle weakness in awake volunteers; Neostigmine induced muscle weakness in awake volunteers; Anaesthesiology - Anaesthetics; Neurological - Studies of the normal brain and nervous system

• Registration Number: ACTRN12617001505392
• Lead Sponsor: Australian Society of Anaesthetists

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2017-10-25
• Last Update Posted: 12 November 2018

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 21

Inclusion Criteria

We recruited healthy volunteers with American Society of Anesthesiologists (ASA) class I physical status to participate in the study.

Exclusion Criteria

Pregnancy, history of neuromuscular or respiratory disease, or any condition that may interfere from the conduct of the study, such as allergy to the study medications or adhesive gel electrodes, currently taking any medication that may affect neuromuscular or respiratory function, or interfere with the study medications. ASA status equal to or greater than 2,

Study & Design

• Study Type: Interventional
• Study Design: Not specified