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临床试验/CTRI/2023/05/053156
CTRI/2023/05/053156尚未招募不适用

UTILITY OF POINT OF CARE ULTRASOUND TO PREDICT VARICEAL ETIOLOGY INPATIENTS WITH UPPER GASTROINTESTINAL HEMORRHAGE PRESENTING TO THE EMERGENCYDEPARTMENT

Dr Siddhi Naik1 个研究点 分布在 1 个国家目标入组 184 人开始时间: 2023年1月6日最近更新:

试验速览

阶段
不适用
状态
尚未招募
发起方
入组人数
184
试验地点
1
主要终点
Diagnosis of Varices on UGI Scopy

研究概览

简要总结

Upper GI Hemorrhage is a common ED presentation which can often be life threatening. Massive bleeding can cause hypovolemia and shock. Hence, this requires expedited management. Upper GI hemorrhage can be Variceal or Non Variceal. Diagnosis of variceal bleed usually happens at Endoscopy. Early identification of variceal cause of GI bleed in ED will enable early initiation of octreotide/terlipressin and plan for Emergent UGI scopy. However, in the Emergency Department, diagnosis of Portal Hypertension and varices is challenging. Use of non-invasive predictors of varices including ultrasound parameters by radiologists have found promising results. But, such a study is lacking in the emergency setting. We would like to study if using a non-invasive, easily accessible, bedside POCUS will help us predict varices in patients presenting to the ED with UGI Hemorrhage. Patients who come to the Emergency Department with upper GI bleed, meeting the inclusion and exclusion criteria will be considered for the study. After taking informed consent, patients will be enrolled. The history and physical examination findings will be noted. Point of care ultrasound will be done measuring the portal vein diameter, portal vein patency and blood flow velocity, portal vein congestion index will be calculated. Splenic diameter will be noted.Details will be collected as per proforma. Laboratory markers as sent by treating clinician will be noted. No additional blood test will be sent other than as clinically indicated. No charge will be levied for the point of care ultrasound. All patients with upper gastrointestinal hemorrhage undergo upper GI scopy by gastroenterologist. The findings of the Upper GI scopy, the discharge diagnosis and outcome will be noted. Through this study, our objectives are 1. To assess Diagnostic accuracy of portal vein indices in point of care ultrasound to predict variceal etiology in patients with upper gastrointestinal hemorrhage presenting to the Emergency Department. 2.To compare point of care ultrasound with laboratory markers to predict variceal etiology in patients with upper gastrointestinal hemorrhage presenting to the Emergency Department.

研究设计

研究类型
Observational

入排标准

年龄范围
18.00 Year(s) 至 99.00 Year(s)(—)
性别
All

入选标准

  • All patients presenting with upper GI Bleed.

排除标准

  • Patients not consenting to get enrolled in the study;
  • Patients not undergoing UGI scopy.
  • Patients who have portal vein thrombosis.

结局指标

主要结局

Diagnosis of Varices on UGI Scopy

时间窗: Point of care ultrasound done at admission to Emergency Department | Upper GI scopy report will be collected once UGI scopy completed (within 48hr)

次要结局

  • Comparing point of care ultrasound with laboratory markers to predict variceal etiology in patients(with upper gastrointestinal hemorrhage presenting to the Emergency Department.)

研究者

发起方
Dr Siddhi Naik
申办方类型
Other [self]

研究点 (1)

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