Unexpected ABR Results in Patients Suspected With Auditory Neuropathy Spectrum Disorder

Not Applicable

Completed

• Conditions: Auditory Neuropathy

• Registration Number: NCT06125015
• Lead Sponsor: Istanbul Medipol University Hospital

Brief Summary

This study aimed to assess the clinical evaluations and potential underlying pathologies in patients diagnosed with Auditory Neuropathy Spectrum Disorder (ANSD) who exhibited unusual results in audiological tests. The research involved the retrospective analysis of audiological tests of 11 patients conducted by expert audiologists at Istanbul Medipol Mega Hospital between 2010 and 2020. These patients displayed abnormalities in their Auditory Brainstem Response (ABR) tests. The study sought to investigate patients with ANSD who presented atypical audiological findings, shedding light on the associated clinical aspects and potential causes of such anomalies.

Detailed Description

Not available

Study Timeline

• Study Start: 2015-01-20
• Primary Completion: 2021-11-30
• Study Completion: 2021-11-30
• Status Verified: 2023-11
• Study First Submitted: 2023-11-04
• Study First Submitted QC: 2023-11-04
• Last Update Submitted: 2023-11-04
• Study First Posted: 2023-11-09
• Last Update Posted: 2023-11-09

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 11

Inclusion Criteria

• Presence of wave V with cochlear microphonics

Exclusion Criteria

• Type B tympanogram

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Primary Outcome Measures

Name	Time	Method
Measuring Hearing Thresholds with Electrophysiological Tests	6 years	Participants' hearing thresholds and cochlear microphonics evaluated by using Auditory Brainstem Responses and Otoacoustic Emissions.
Evaluating Middle Ear Pathologies	6 years	Participants' middle ear pathologies evaluated by using Tympanometry
Evaluating Hearing Thresholds by Using Behavioral Tests	6 years	Participants' reactions to sounds were assessed using Free Field Audiometry or headphones. These evaluations were conducted initially at the time of diagnosis and subsequently after the patients had started using hearing aids.