Effectiveness of postoperative radiotherapy in patients with oral or oropharyngeal squamous cell carcinoma and histologically confirmed single ipsilateral lymphnode metastasis (pN1)
Phase 4
Completed
- Conditions
- head-neck cancer metastasisoral cancer1002747610019190
- Registration Number
- NL-OMON30589
- Lead Sponsor
- Academisch Medisch Centrum
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 12
Inclusion Criteria
pT1/T2 oral or oropharyngeal cancer
pN1 nodal metastasis
Complete surgical resection
Patient agreement
Karnovsky > 50
Exclusion Criteria
Pregnancy
< 18 years
Karnovsky <50
legally incapable
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>5-year survival</p><br>
- Secondary Outcome Measures
Name Time Method <p>Recurrence of tumour (local, regional, distant)<br /><br>Quality of life<br /><br>Treatment Costs</p><br>
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What molecular pathways are targeted by postoperative radiotherapy in pN1 oral/oropharyngeal squamous cell carcinoma?
How does postoperative radiotherapy compare to standard-of-care chemoradiotherapy for pN1 head-neck cancer metastasis?
Which biomarkers (e.g., HPV status, p16 expression) predict response to radiotherapy in pN1 oral SCC patients?
What are the long-term adverse events associated with postoperative radiotherapy in pN1 oropharyngeal cancer survivors?
Are there combination therapies with radiotherapy improving outcomes for pN1 squamous cell carcinoma of the head and neck?