Shatavaryadi churna in the treatment of Mutrashmari

Completed

• Conditions: Urinary calculus, unspecified. Ayurveda Condition: Mutrashmari,

• Registration Number: CTRI/2021/01/030273
• Lead Sponsor: Dr Anisha S Ashraf

Brief Summary

Mutrashmari which is one of the ashta mahagada is the most common disorders of mutravaha srotas. Though Ayurveda is effectively being used to manage it, it is the need of hour to develop a few evidence based formulations.

Here six drugs are mixed together in equal quantity and 6 grams twice daily after food is given with tamarind juice for 21 days. The trial medicine contains the following drugs namely Shatavari, Gokshura, Kulattha, Punarnava, Varuna and Ushira. These drug are having Vedana

Shamaka, Mutrala and Ashmari Bhedana actions. Hence the clinical study was undertaken to evaluate the effect of Shatavaryadi Churna over the subjective and

objective parameters of Mutrashmari.

OBJECTIVE : The main objective of the study is to evaluate the efficacy of Shatavaryadi Churna in the management of Mutrashamari with special reference to Urolithiasis.

METHODOLOGY: Inerventional clinical study.

Drug dosage: All the six drugs in Churna form will be mixed together and 6 grams

twice daily after food for 21 days.

Anupana : Amlika swarasa (Tamarind juice)

Duration: Total duration of study was 28 days.

Follow up:

First follow up – 7th day

Second follow up – 14th day

Third follow up – 21st day

After treatment follow up – 28th day

RESULT :

Shatavaryadi Churna shown significant reduction in pain abdomen, radiating pain, burning micturition, obstruction to the flow of urine, expulsion of calculi,

reduction in number of calculi and reduction in size of calculi after the treatment.

CONCLUSION :

• The drug Shatavaryadi Churna shown significant improvement in both subjective and objective parameters.

• Marked relief was obtained in pain abdomen, radiating pain, burning micturition and obstruction to the flow of micturition.

• In current study, reduction in size and number of calculi had shown significant difference.

• The drug has shown overall relief in symptoms of the Mutrashmari.

Detailed Description

Not available

Study Timeline

• Study Start: 2021-06-01
• Study Completion: 2022-03-01
• Last Update Posted: 2023-11-05

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

• Size of Ashmari less than 10 mm.
• Age group between 18-70 years irrespective of gender, occupation, race and socio economic status.
• Ureteric calculi, vesical calculi and renal calculi are included.
• Multiple calculi less than or equal to 3 Those patients who are ready to undergo treatment as per protocol & who are ready to sign the informed consent form.

Exclusion Criteria

• Patients who are known case of severe systemic disorders like renal failure, tuberculosis, polycstic kidney and neoplasms.
• Pregnant and lactating women.
• Type I and Type II diabetes mellitus HIV, HBsAg Subjects with gouty arthritis.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Before and after treatment check for	21 days
Mehato Vedana in Nabhi Pradesha, Basti Pradesha, Seevani Pradesha, Mehana Pradesha (Pain while micturition)	21 days
Mutradaha (Burning micturition)	21 days
Sarudhira Mutrata (Haematuria)	21 days
Mutradhara Sanga (Obstructionto the flow of micturition/ frequency)	21 days

Secondary Outcome Measures

Name	Time	Method
Before and after treatment check for	Mehato Vedana in Nabhi Pradesha, Basti Pradesha, Seevani Pradesha, Mehana Pradesha (Pain while micturition)

Trial Locations

Locations (1)

SDM COLLEGE OF AYURVEDA AND HOSPITAL; 🇮🇳 Hassan, KARNATAKA, India

SDM COLLEGE OF AYURVEDA AND HOSPITAL

🇮🇳Hassan, KARNATAKA, India

Dr Anisha S Ashraf

Principal investigator

9495442136

pg19163@sdmcahhassan.org