Evaluation of Ocular Surface Tumors Using Anterior Segment Optical Coherence Tomography (OCT)

Not yet recruiting

• Conditions: Ocular Surface Tumors

• Registration Number: NCT06808126
• Lead Sponsor: Assiut University

Brief Summary

optical coherence tomography (OCT) can scan a range of ocular tissues and take high-resolution image sections during ophthalmic examination..

and recommended as a rapid, informative and quite reliable method of examination to differentiate benign from malignant ocular surface tumors.

The conjunctiva is an anatomical site with a prominent risk of squamous cell carcinoma development, which is a unique biological behavior. The superficial lesion with significant epithelial cell growth usually displays unique data, contributing to unusual ocular tumors.

Anterior segment optical coherence tomography (AS-OCT), as a noninvasive, high-resolution imaging technique, provides crucial morphological and anatomical information in ocular surface tumors via visualizing the layer structure of the cornea and anterior segment, qualifying tumor morphology, and quantifying thickness and extension. AS-OCT can provide valuable information for helping in clinical diagnoses, differential diagnoses, prognoses, and evaluating responses to treatments as a significant imaging tool in ocular surface tumors.

The correct diagnosis and classification of ocular surface tumors are crucial aspects of their proper management.

the aim of the study • To evaluate the imaging characteristics of ocular surface tumors on high-resolution anterior segment optical coherence tomography (ASOCT).

Detailed Description

optical coherence tomography (OCT) can scan a range of ocular tissues and take high-resolution image sections during ophthalmic examination..

and recommended as a rapid, informative and quite reliable method of examination to differentiate benign from malignant ocular surface tumors.

The conjunctiva is an anatomical site with a prominent risk of squamous cell carcinoma development, which is a unique biological behavior. The superficial lesion with significant epithelial cell growth usually displays unique data, contributing to unusual ocular tumors.

Anterior segment optical coherence tomography (AS-OCT), as a noninvasive, high-resolution imaging technique, provides crucial morphological and anatomical information in ocular surface tumors via visualizing the layer structure of the cornea and anterior segment, qualifying tumor morphology, and quantifying thickness and extension. AS-OCT can provide valuable information for helping in clinical diagnoses, differential diagnoses, prognoses, and evaluating responses to treatments as a significant imaging tool in ocular surface tumors.

The correct diagnosis and classification of ocular surface tumors are crucial aspects of their proper management.

the aim of the study • To evaluate the imaging characteristics of ocular surface tumors on high-resolution anterior segment optical coherence tomography (ASOCT).

Study Timeline

• Status Verified: 2025-01
• Study First Submitted: 2025-01-29
• Study First Submitted QC: 2025-01-29
• Last Update Submitted: 2025-01-29
• Study First Posted: 2025-02-05
• Last Update Posted: 2025-02-05
• Study Start: 2025-03-01
• Primary Completion: 2026-03-01
• Study Completion: 2026-05-01

Recruitment & Eligibility

• Status: NOT_YET_RECRUITING
• Sex: All
• Target Recruitment: 58

Inclusion Criteria

• all patients presented with ocular surface lesion suspected to be neoplastic

Exclusion Criteria

• all patients presented with ocular surface lesion proved by pathology not to be neoplastic

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
the accuracy of oct	baseline	the accuracy of oct in diagnosis of Ocular Surface Tumors