Are probiotics useful post-tonsillectomy? – A randomised controlled study (feasibility trial)

Phase 3

Completed

• Conditions: Pain post tonsillectomy; Secondary post tonsillectomy haemorrhage; Surgery - Other surgery; Anaesthesiology - Pain management

• Registration Number: ACTRN12619001474145
• Lead Sponsor: Frankston Hospital

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2019-10-24
• Study Completion: 2021-01-12
• Last Update Posted: 19 April 2022

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

Age 18-55
- Elective Tonsillectomy or adenotonsillectomy only
- Indication of operation (one of the following): asymmetric tonsillar enlargement, recurrent tonsillitis, previous quinsy (> one), sleep disordered breathing, halitosis, tonsillolith
- Weight must be more than 50kg.

Exclusion Criteria

Allergic to opioids / codeine / Endone™ / paracetamol
Lactose intolerance
Unstable metabolic diseases/disorder
Heart failure or a history of endocarditis
Immunocompromised
Kidney disease
Liver disease
Hemorrhagic diathesis
Other concomitant surgical procedures.
Pregnancy
Patients who are currently taking NSAIDs e.g.: Celebrex™, Aspirin, etc.
Patients who are on regular opiates or Paracetamol
Recent use of probiotics within 1 month

Study & Design

• Study Type: Interventional
• Study Design: Not specified