ITMCTR2100004463RecruitingPhase 1
Study on the characteristics of intestinal microecological community and its correlation with syndromes in patients with early age-related macular degeneration (AMD)
Eye Hospital, China Academy of Chinese Medical Sciences0 sitesStarted: TBDLast updated:
Trial Snapshot
- Phase
- Phase 1
- Status
- Recruiting
- Sponsor
Study Overview
Brief Summary
No summary available.
Study Design
- Study Type
- Observational study
Eligibility Criteria
- Ages
- 50 to 80 (—)
- Sex
- All
Inclusion Criteria
- •AMD patients group
- •1. In accordance with the diagnostic criteria of early AMD: Beckman initiative for macular research classification committee-Clinical classification of age-related macular degeneration and Clinical pathway of age-related macular degeneration in China
- •2. Aged 50 to 80 years;
- •3. Agree to participate in the trial and provide written informed consent.
- •Control group
- •1. Aged 50 to 80 years;
- •2. Those without AMD-related pathological changes, glaucoma, uveitis or other fundus diseases, which involves the macular area and retinal vessels;
- •3. Those without diabetes, hypertension, malignant tumors, mental diseases, immune system diseases and other diseases, all indicators of physical examination are within the normal range;
- •4. Those without infectious diseases or antibiotics taken in the past 4 weeks;
- •5. Those without any intestinal related diseases including acute gastroenteritis in the past 4 weeks;
- •6. Those without having taken probiotics/prebiotics or other micro-ecological regulators, Chinese medicines (including Chinese patent medicine, decoctions with clear ingredients, or remedies with unknown ingredients) in the past 4 weeks, or overeating foods with antibacterial effects (such as chili,ginger,garlic,etc.);
- •7. Agree to participate in the trial and provide written informed consent.
Exclusion Criteria
- •AMD patients group
- •1. Those with diabetes,hypertension,malignant tumors,mental diseases,immune system diseases and other diseases;
- •2. Those with glaucoma,uveitis or other fundus diseases,which involves the macular area and retinal vessels;
- •3. Those with infectious diseases or antibiotics taken in the past 4 weeks;
- •4. Those with any intestinal related diseases including acute gastroenteritis in the past 4 weeks;
- •5. Those with having taken probiotics/prebiotics or other micro-ecological regulators, Chinese medicines (including Chinese patent medicine, decoctions with clear ingredients,or remedies with unknown ingredients) in the past 4 weeks,or overeating foods with antibacterial effects (such as chili, ginger,garlic,etc.);
- •6. Those with other stages of AMD.
Investigators
Similar Trials
Not yet recruiting
Phase 1
Study on the intestinal microflora characteristics and TCM syndromes of patients with hepatocellular carcinoma complicated with intestinal dysfunctioPrimary hepatic carcinomaITMCTR2200005950Changhai Hospital
Recruiting
Phase 1
Based on the association study of intestinal microecology and TCM tongue diagnosis study on the establishment of a precise diagnosis and treatment system for membranous nephropathy in traditional Chinese medicineITMCTR2100004625onghua Hospital Affiliated to Shanghai University of Traditional Chinese Medicine
Recruiting
Phase 1
Study on the intestinal microecology with ''Formula Syndrome'' of TCM for diarrehea-predominant pattern irritable bowel syndrome by the technology of metagenomicsirritable bowel syndrome-DiarrheaITMCTR2100004775Chengdu University of Traditional Chinese Medicine
Completed
Not Applicable
Sarcopenia and Intestinal MicrobiomeDiseases of the musculoskeletal system and connective tissueKCT0005905The Catholic University of Korea, St. Vincent's Hospital60
Recruiting
Not Applicable
Gastrointestinal micro and mycobiome profile in chemotherapy and stem cell transplantation for hematological malignanciesHematological malignancies (acute leukemia and malignant lymphoma)JPRN-UMIN000027086Chiba University Hospital200