Observational Study to Assess Genotypes/Phenotypes Correlations in Type-2 Diabetic Retinopathy
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Type-2 Diabetic Retinopathy
- Sponsor
- Association for Innovation and Biomedical Research on Light and Image
- Enrollment
- 400
- Locations
- 1
- Primary Endpoint
- Phenotypes of Diabetic Retinopathy progression.
- Status
- Completed
- Last Updated
- 10 years ago
Overview
Brief Summary
The purpose of this study is to characterize type 2 diabetic patients with initial alterations of diabetic retinopathy (DR) based on 3 different phenotypes previously identified and different patterns of progression in order to correlate this data with genetic information.
Detailed Description
This study aims to to characterize type 2 diabetic patients with initial alterations of diabetic retinopathy (DR) based on three different phenotypes previously identified and different patterns of progression \[Lobo, 2004\] in order to correlate this data with genetic information (based on a list of candidate genes previously identified as being involved in DR). The results of this study will be used exclusively for scientific purposes.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Type-2 diabetic subjects form the PTDC/SAU-OSM/72635/2006 clinical trial (early stages of non-proliferative retinopathy - level 30 to 35 ETDRS;. females or males; age over 18 years) with a signed Informed Consent for this study.
Exclusion Criteria
- •Cataract or other eye disease that may interfere with fundus examinations; Vitreous syneresis or posterior vitreous detachment; and Dilatation of the pupil \< 5 mm.
Outcomes
Primary Outcomes
Phenotypes of Diabetic Retinopathy progression.
Time Frame: June 2011