Observational Study to Assess Genotypes/Phenotypes Correlations in Type-2 Diabetic Retinopathy
- Conditions
- Type-2 Diabetic Retinopathy
- Registration Number
- NCT01228981
- Lead Sponsor
- Association for Innovation and Biomedical Research on Light and Image
- Brief Summary
The purpose of this study is to characterize type 2 diabetic patients with initial alterations of diabetic retinopathy (DR) based on 3 different phenotypes previously identified and different patterns of progression in order to correlate this data with genetic information.
- Detailed Description
This study aims to to characterize type 2 diabetic patients with initial alterations of diabetic retinopathy (DR) based on three different phenotypes previously identified and different patterns of progression \[Lobo, 2004\] in order to correlate this data with genetic information (based on a list of candidate genes previously identified as being involved in DR).
The results of this study will be used exclusively for scientific purposes.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 400
- Type-2 diabetic subjects form the PTDC/SAU-OSM/72635/2006 clinical trial (early stages of non-proliferative retinopathy - level 30 to 35 ETDRS;. females or males; age over 18 years) with a signed Informed Consent for this study.
- Cataract or other eye disease that may interfere with fundus examinations; Vitreous syneresis or posterior vitreous detachment; and Dilatation of the pupil < 5 mm.
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Phenotypes of Diabetic Retinopathy progression. June 2011
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
AIBILI - Clinical Trials Center
🇵🇹Coimbra, Portugal