Probiotic Lozenge for dental caries preventio
Not Applicable
Active, not recruiting
- Conditions
- subjects have caries ≤ two teeth,have an absence of periodontal disease,be a non-smoker,and have daily tooth brushing habits using a fluoride containing toothpaste.caries prevention,probioticmutan streptococci
- Registration Number
- TCTR20180808004
- Lead Sponsor
- ational Innovation Agency
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Active, not recruiting
- Sex
- All
- Target Recruitment
- 120
Inclusion Criteria
subjects aged 12-14 years old, have caries ≤ two teeth, have an absence of periodontal disease, be a non-smoker, and have daily tooth brushing habits using a fluoride containing toothpaste.
Exclusion Criteria
having habitual consumption of probiotics or xylitol, having systemic antibiotic medication taken within 6 weeks, having an allergy to cows’ milk, lactose intolerance, and any severe food allergy, (d) having systemic or severe chronic diseases, and undergoing orthodontic treatment.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Cariogenic bacteria 4, 8 weeks Cariogenic bacteria level by real time PCR
- Secondary Outcome Measures
Name Time Method side effect; diarrhoea, vomiting, fever 8 weels interview