临床试验/NCT01100671

NCT01100671已完成不适用

Comparison of 18F-fluorodeoxyglucose Positron Emission Tomography and Coronary Computed Tomography in Assessing Vascular Inflammation in Healthy Population

Korea University1 个研究点分布在 1 个国家目标入组 120 人开始时间: 2010年4月最近更新: 2018年3月14日

适应症

试验速览

阶段: 不适用
状态: 已完成
发起方: Korea University
入组人数: 120
试验地点: 1
主要终点: Correlation between vascular inflammatory status measured by 18FDG PET and MDCT

研究概览研究设计入排标准结局指标研究者研究点记录与标识符相似试验

研究概览

简要总结

Vascular inflammation is a key factor in both the pathogenesis and outcome of atherosclerosis. 18F-fluorodeoxyglucose (FDG) positron emission tomography (PET) is a promising tool for identifying and quantifying vascular inflammation within atherosclerotic plaques.cardiac multidetector-row CT can provide measurements of coronary artery calcium (CAC), the degree of stenosis, and the characteristics of plaque including its potential vulnerability. Therefore, the purpose of the investigators study is to compare the usefulness of 18 FDG-PET and MDCT in assessing the vascular inflammatory status and vulnerability.

研究设计

研究类型: Observational
观察模型: Cohort
时间视角: Cross Sectional

入排标准

年龄范围: 20 Years 至 80 Years（Adult, Older Adult）
性别: All
接受健康志愿者: 是

入选标准

•Healthy patients for visiting routine medical check in our clinic

排除标准

•History of cardiovascular disease (myocardial infarction, unstable angina, stroke, or cardiovascular revascularization)
•Stage 2 hypertension (resting blood pressure, ≥ 160/100 mmHg)
•Malignancy
•Severe renal or hepatic disease
•Subjects taking medications that might affect inflammation such as NSIAD and statin

结局指标

主要结局

Correlation between vascular inflammatory status measured by 18FDG PET and MDCT

时间窗: 20weeks

次要结局

Comparison the correlation with inflammatory marker and vascular inflammatory status assessed by 18FDG PET and MDCT(20 weeks)

研究者

发起方

Korea University

申办方类型

Other

责任方

Principal Investigator

主要研究者

Kyung Mook Choi

Professor

Korea University

研究点 (1)

Loading locations...

相似试验

已完成

不适用

Metabolic Imaging in Carotid AtherosclerosisStrokeAtherosclerosis

NCT01674257University of Edinburgh26

已完成

不适用

Arterial wall inflammation measured with 18F-FDG PET/CT in patientswith statin intolerance before and after treatment with a PCSK-9 inhibitor

NL-OMON20315niversity of Amsterdam50

已完成

2 期

Arterial wall inflammation measured with 18F-FDG PET/CT in patients with statin intolerance before and after treatment with a PCSK-9 inhibitorAtherosclerosis

NL-OMON45376Vasculaire geneeskunde, Academisch Medisch Centrum53

撤回

不适用

Arterial wall inflammation measured with 18F-FDG PET/CT in patients with familial hypercholesterolemia before and after treatment with a PCSK-9 inhibitoratherosclerosis

NL-OMON43194Academisch Medisch Centrum52

进行中（未招募）

1 期

Arterial wall inflammation measured with 18F-FDG PET/CT in patients with statin intolerance before and after treatment with a PCSK-9 inhibitorPatients with CV-risk and statin intolerance due to statin-associated muscle symptoms (SAMS)

EUCTR2016-004794-41-NLAcademical medical centre, dep of internal medicine