Comparison of 18F-fluorodeoxyglucose Positron Emission Tomography and Coronary Computed Tomography in Assessing Vascular Inflammation
Completed
- Conditions
- Atherosclerosis
- Interventions
- Other: Cross section study
- Registration Number
- NCT01100671
- Lead Sponsor
- Korea University
- Brief Summary
Vascular inflammation is a key factor in both the pathogenesis and outcome of atherosclerosis. 18F-fluorodeoxyglucose (FDG) positron emission tomography (PET) is a promising tool for identifying and quantifying vascular inflammation within atherosclerotic plaques.cardiac multidetector-row CT can provide measurements of coronary artery calcium (CAC), the degree of stenosis, and the characteristics of plaque including its potential vulnerability. Therefore, the purpose of the investigators study is to compare the usefulness of 18 FDG-PET and MDCT in assessing the vascular inflammatory status and vulnerability.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 120
Inclusion Criteria
- Healthy patients for visiting routine medical check in our clinic
Exclusion Criteria
- History of cardiovascular disease (myocardial infarction, unstable angina, stroke, or cardiovascular revascularization)
- Diabetes
- Stage 2 hypertension (resting blood pressure, ≥ 160/100 mmHg)
- Malignancy
- Severe renal or hepatic disease
- Subjects taking medications that might affect inflammation such as NSIAD and statin
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description Healthy patients Cross section study -
- Primary Outcome Measures
Name Time Method Correlation between vascular inflammatory status measured by 18FDG PET and MDCT 20weeks
- Secondary Outcome Measures
Name Time Method Comparison the correlation with inflammatory marker and vascular inflammatory status assessed by 18FDG PET and MDCT 20 weeks
Trial Locations
- Locations (1)
Hye Jin Yoo
🇰🇷Seoul, Korea, Republic of