DOES THE ADDITION OF PREGABALIN AND S-KETAMINE TO LOCAL KNEE INFILTRATION, IMPROVE THE POSTOPERATIVE KNEE FUNCTION OUTCOME AFTER TOTAL KNEE ARTHROPLASTY?

Recruiting

• Conditions: posoperative analgesia after total knee arthroplasty; 10005944

• Registration Number: NL-OMON36143
• Lead Sponsor: niversitair Medisch Centrum Sint Radboud

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 29 April 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: Not specified
• Target Recruitment: 60

Inclusion Criteria

patients scheduled for total knee arthroplasty

Exclusion Criteria

patient refusal; preexisting neurological or psychiatric illnesses; chronic pain syndrome; alcohol or drug abuse; SUSPECTED POSSIBILITY OF POSTOPERATIVE DELIRIUM , difficulties in communication or expected inability to understand patient-controlled analgesia; rheumatoid arthritis, revision knee surgery or participation in another study.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>PRIMARY PARAMETER IS:<br /><br>Range of motion / Knee flexion angle<br /><br><br /><br>The knee flexion angle is measured from the first postoperative day (Day 1),<br /><br>until the day of discharge (DD), by a physical therapist as (flexion_1,flexion<br /><br>_2, flexion_3, flexion_4, flexion_5, flexion_DD). </p><br>