Value of Amphotericin B Inhalation for Prophylaxis of Invasive Pulmonary Aspergillosis After Renal Transplantation

Phase 4

• Conditions: Invasive Pulmonary Aspergillosis

• Registration Number: NCT00986713
• Lead Sponsor: Capital Medical University

Brief Summary

The purpose of this study is to determine whether inhalation with aerosolized amphoterin B 10mg/d is more effective than aerosolized amphoterin B 2mg/d to reduce the incidence of invasive pulmonary aspergillosis.

Detailed Description

Not available

Study Timeline

• Study Start: 2008-06
• Status Verified: 2009-09
• Study First Submitted: 2009-09-29
• Study First Submitted QC: 2009-09-29
• Last Update Submitted: 2009-09-29
• Study First Posted: 2009-09-30
• Last Update Posted: 2009-09-30
• Primary Completion: 2010-09
• Study Completion: 2010-10

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 400

Inclusion Criteria

• 65ys≥age≥18ys
• renal transplant recipients

Exclusion Criteria

• subjects with hypersensitivity to amphotericin B
• receipt of inhalational or intravenous amphotericin B within last 30 days
• subjects with known invasive fungal infection before renal transplant
• subjects with pneumonia

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
invasive pulmonary aspergillosis	3 years

Trial Locations

Locations (1)

Beijing Chaoyang Hospital,Affiliate of Capital Medical University; 🇨🇳 Beijing, Beijing, China