sing ultrasonographicparameters to assess diameter of major blood vessels using abdominal scanpreoperatively and using it to associate with intraoperative hypotension after spinalanesthesia in patients with diabetes mellitus

Not Applicable

Completed

• Conditions: Health Condition 1: - Health Condition 2: E115- Type 2 diabetes mellitus with circulatory complications

• Registration Number: CTRI/2020/08/027017
• Lead Sponsor: JIMER intramural research fund committee

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Completion: 2021-08-31
• Last Update Posted: 24 November 2021

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 120

Inclusion Criteria

GROUP C

Adults without diabetes mellitus above 18 years of age belonging to both sexes undergoing elective surgeries under spinal anesthesia

Patients belonging to American society of Anesthesiologists status 1 or 2

BMI 18.5 -30

GROUP D

Adults with diabetes mellitus above 18 years of age belonging to both sexes undergoing elective surgeries under spinal anesthesia BMI18.5 -30 Patients belonging to American Society of Anesthesiologists status 2 or 3

Exclusion Criteria

GROUP C

Patient refusal for spinal anesthesia.

Patient taking drugs affecting sympathetic and parasympathetic function

Patients with other comorbidities

Patient in whom more than 500ml of blood loss is anticipated

Patients with coagulopathy

Pregnant patients

GROUP D

Patient refusal for spinal anesthesia.

Patient taking drugs affecting sympathetic and parasympathetic function

Patients with other comorbidities other than diabetes

Patient in whom more than 500ml of blood loss is anticipated

Patients with coagulopathy

Pregnant patients

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To measure Caval Aorta index (IVC:AO INDEX) and to compare the odds ratio between the groups for incidence of postspinal hypotensionTimepoint: In the preop holding area ultrasound will be performed and the caval aorta index will be measured. . Patient will receive spinal anasthesia.Hemodynamic parameters will be recorded every 2.5 minutes for the first 10 minutes and every 5 minutes till the end of surgery.

Secondary Outcome Measures

Name	Time	Method
To measure IVC collapsibility index and to compare the odds ratio between the groups for the incidence of post spinal hypotension <br/ ><br>To compare the requirement of vasopressor between the groups <br/ ><br>Timepoint: In the preop holding area ultrasound will be performed and the ivc collapsibility index will be measured. . Patient will receive spinal anasthesia.Hemodynamic parameters will be recorded every 2.5 minutes for the first 10 minutes and every 5 minutes till the end of surgery.