Clinical Use of Magnetic Resonance Perfusion Imaging to Qualitatively Assess Adequate Distal Perfusion After Endovascular Revascularization in Critical Limb Ischemia
Completed
- Conditions
- IschemiaLower LimbPerfusion
- Interventions
- Procedure: Magnetic Resonance Perfusion Imaging
- Registration Number
- NCT02646150
- Lead Sponsor
- Seung-Whan Lee, M.D., Ph.D.
- Brief Summary
This study evaluates the clinical effectiveness of Magnetic Resonance(MR) perfusion imaging to qualitatively assess adequate distal perfusion after endovascular revascularization in Critical Limb Ischemia
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 65
Inclusion Criteria
- Age 20 and above
- Critical limb ischemia with ulcer
- Ankle brachial index(ABI) ≤ 0.9 or Toe brachial index (TBI) ≤ 0.5 or Transcutaneous oxygen pressure (TcPo2) ≤ 40mmHg
- ≥ 70 percentage of stenosis of infrapopliteal artery on lower extremity computed tomography angiography or lower extremity doppler
- Subject understands protocol and provides written, informed consent
Exclusion Criteria
- Post-traumatic critical limb ischemia
- Neurogenic limb ischemia
- Life expectancy ≤ 2 years
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description critical limb ischemia Magnetic Resonance Perfusion Imaging -
- Primary Outcome Measures
Name Time Method The change of deoxyhemoglobin in MR imaging 6 months
- Secondary Outcome Measures
Name Time Method The event rate of unplanned major and minor amputation in limb 6 months The event rate of complete healing of lower extremity ulcer 6 months
Trial Locations
- Locations (1)
Asan Medical Center
🇰🇷Seoul, Korea, Republic of