Effect of aging on metabolism and on clinical outcome after colorectal surgery. Assessment of preoperative riskfactors on postoperative morbidity and mortality.

• Conditions: aging; elderly patient; 10017990; 10037008; 10017998

• Registration Number: NL-OMON30212
• Lead Sponsor: Catharina-ziekenhuis

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 13 May 2024

Recruitment & Eligibility

• Status: Pending
• Sex: Not specified
• Target Recruitment: 100

Inclusion Criteria

• Admission for elective abdominal surgery for colon or rectal carcinoma.
• Age: >55 years.
• Fit for elective surgery as defined by ASA score.
• Having obtained his/her informed consent

Exclusion Criteria

Younger than 55 years

Study & Design

• Study Type: Observational non invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Infectious complications (fever, pneumonia, sepsis, bacteraemia, intrathoracic<br /><br>or intra-abdominal infection, major wound infection, central-line infection,<br /><br>urinary-tract infection); non-infectious complications as CV-complications<br /><br>(infarct, cardiac failure, cerebrovascular accident, deep venous thrombosis,<br /><br>hypotension and infarct), re-operation, transfusion-needed anemia, anastomotic<br /><br>leakage and MOF; nutritional status by weight, BMI, Bioelectrical Impedance<br /><br>Analysis (LBM, skeletal body mass, ECF, ICF, TBW) and metabolic status by and<br /><br>amino acid profiles, CRP, albumin, glucose, insulin, fructosamine, HbA1c and<br /><br>ADMA. </p><br>

Secondary Outcome Measures

Name	Time	Method
<p>not applicable</p><br>