Dynamic Interaction of Obesity, Age, and Inflammatory Marker With the Severity of Knee Osteoarthritis

Completed

• Conditions: Patients with knee osteoartrithis; Interaction, Obesity, Age, Inflammation, Knee Osteoarthritis

• Registration Number: TCTR20220919005
• Lead Sponsor: M. Nasser Mustari

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Completion: 2021-01-31
• Study Start: 2022-09-19
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 80

Inclusion Criteria

The inclusion criteria were knee OA patients who visited the Rheumatology and Internal Medicine outpatient department.

Exclusion Criteria

The exclusion criteria were a history of knee surgery, a history of other arthritis, and a history of knee joint trauma.

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Serum levels of INF gamma, IL1a, IL1b, IL1RA, IL4, IL8, MCP-1, and TNFa Briefly, venous blood samples were obtained from patients with knee osteoarthritis who visited the Rheumatology and Internal Medicine outpatient department ELISA

Secondary Outcome Measures

Name	Time	Method
Demographic data Demographic data were obtained from patients with knee osteoarthritis who visited the Rheumatology and Internal Medicine outpatient department Patient reported outcome using a questionnaire interview