Does Transfer of Poor-quality Embryos With Good-quality Embryos Improve Pregnancy Outcome in Women Undergoing IVF/ICSI?
Not Applicable
Completed
- Conditions
- Infertility
- Interventions
- Other: Embryo transfer
- Registration Number
- NCT03113097
- Lead Sponsor
- Ain Shams University
- Brief Summary
Women planned to undergo blastocyst-stage embryo transfer after IVF/ICSI were randomized into 2 groups:
* group I: women who had only good-quality embryo transfer.
* group II: women who had both good-quality and poor-quality embryo transfer.
primary outcome was ongoing clinical pregnancy rate
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- Female
- Target Recruitment
- 627
Inclusion Criteria
- women undergoing primary IVF/ICSI cycles for tubal factor/unexplained infertility and had blastocyst-stage ET
Exclusion Criteria
- cleavage-stage ET.
- women who had no good-quality embryos to transfer
- women who had known poor endometrial receptivity
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description good- and poor-quality embryo transfer Embryo transfer Women who had both good- and poor-quality embryo transfer Good-quality embryo transfer Embryo transfer Women who had only good-quality embryo transfer
- Primary Outcome Measures
Name Time Method Ongoing clinical pregnancy rate 12 weeks viable intrauterine pregnancy ongoing beyond 12 weeks of gestation
- Secondary Outcome Measures
Name Time Method Biochemical pregnancy rate 2 weeks after ET positive serum hCG
Clinical pregnancy rate 4 weeks after ET sonographic detection of viable intrauterine gestational sac
Multiple pregnancy rate 4-6 weeks after ET No. of intrauterine gestational sacs
Ectopic pregnancy rate 6 weeks after ET Extrauterine pregnancy