Skip to main content
MedPathMedPath Home
Clinical Trials/DRKS00030633
DRKS00030633
Recruiting
Not Applicable

Cerebral amyloid angiopathy and clinical phenotype of Alzheimer's disease: a prospective multimodality imaging study - CAADMI

Klinik für Neurologie Uniklinik RWTH Aachen0 sites40 target enrollmentMarch 21, 2023
Share to TwitterShare to FacebookShare to LinkedInShare to Reddit
ConditionsF00I68.0Dementia in Alzheimer diseaseCerebral amyloid angiopathy

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
F00
Sponsor
Klinik für Neurologie Uniklinik RWTH Aachen
Enrollment
40
Status
Recruiting
Last Updated
last year
OverviewInvestigatorsEligibility CriteriaOutcomesSimilar Trials

Overview

Brief Summary

No summary available.

Registry
who.int
Start Date
March 21, 2023
End Date
TBD
Last Updated
last year
Study Type
Observational
Sex
All

Investigators

Sponsor
Klinik für Neurologie Uniklinik RWTH Aachen

Eligibility Criteria

Inclusion Criteria

  • •Written declaration of consent from the study participant in the case of capacity to consent

Exclusion Criteria

  • •\- Contraindication for MRI examination
  • •\- Other causes of intracranial haemorrhage or cortical haemosiderosis other than CAA (e.g. acquired or hereditary coagulation or platelet aggregation disorders, intracranial vascular malformations, CNS vasculitis, significant traumatic brain injury).
  • •\- Hereditary AD or hereditary CAA
  • •\- Severity of cognitive impairment according to the Global Deterioration Scale \>\= 5 (GDS; GDS 5 \= moderate dementia)
  • •\- Atypical phenotypic presentation of AD, such as logopenic primary progressive aphasia or posterior cortical atrophy (PCA)

Outcomes

Primary Outcomes

Not specified

Similar Trials

Completed
Not Applicable
Cerebral Amyloid Angiopathy: Vascular Imaging and fluid markers of Amyloid depositioneurodegenerative aandoeningen (vasculair)Cerebral amyloid angiopathysmall vessel disease10007963
NL-OMON42188niversitair Medisch Centrum Sint Radboud100
Recruiting
Not Applicable
SEarchiNg BiomarkErs Cerebral Amyloid Angiopathy (SENECA)Cerebral Amyloid Angiopathy
NCT04204642Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta500
Completed
Not Applicable
Cerebral amyloid angiopathy fluid biomarkers evaluation (CAFE)
NL-OMON46797Radboud Universitair Medisch Centrum50
Completed
Not Applicable
Cerebral amyloid angiopathy fluid biomarkers evaluation - Alzheimer*s Disease (CAFÉ-AD)ziekte van AlzheimerCerebral amyloid angiopathysmall vessel disease10007963
NL-OMON48320Radboud Universitair Medisch Centrum50
Not yet recruiting
Not Applicable
Amyloid pathology and vascular disease in focus: exploring interaction in two pathways towards neurodegenerationeurodegeneratieve aandoeningenDementiavascular pathology10042258
NL-OMON46142Erasmus MC, Universitair Medisch Centrum Rotterdam700