To study the efficacy of intradiscal autologous Platelet rich plasma injection in patients with lumbar disc disease
- Conditions
- Health Condition 1: M511- Thoracic, thoracolumbar and lumbosacral intervertebral disc disorders with radiculopathy
- Registration Number
- CTRI/2023/10/058247
- Lead Sponsor
- Intra mural research fund JIPMER
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
1)Age-18-50yrs
2)Refractory low back pain persisting for 3-12 weeks
3)lumbar disc protrusion or extrusion at single level
4)Maintained intervertebral disk height of at least 50% on MRI
5)Disc protrusion or extrusion seen on MRI corresponding to clinical findings
6)Decreased signal intensity of disc on MRI T2 imaging
7) Type 1 or Type 2 Modic changes of an end-plate on MRI
1)Spinal dysmorphism
2)With neurological deficit
3)Sequestered disc fragments
4)previous surgical intervention for spine
5)Facet arthropathy
6)Sacroiliac joint pain
7)Traumatic spine injury
8)Known bleeding disorder or on anticoagulants or antiplatelet drugs
9) Pregnancy
10)Psychiatric condition
11)Peripheral neuropathy-diabetes with peripheral neuropathy, leprosy, syphilis
12)Tumors
13)Infective discitis
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Change in VAS and FRI scores 3 weeks and 6 weeks post procedure as compared to baselineTimepoint: 1)At baseline <br/ ><br>2)3 weeks post intervention <br/ ><br>3)6 weeks post intervention
- Secondary Outcome Measures
Name Time Method ATimepoint: NA