Spectral CT Combined With MSI for Predicting Regional Lymph Node Metastasis in Gastric Cancer
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
- 发起方
- 入组人数
- 260
- 试验地点
- 1
- 主要终点
- Pathological N stage
研究概览
简要总结
This study prospectively collected spectral CT imaging data and clinical information related to gastric cancer, evaluated the diagnostic efficacy of its image quality for regional lymph nodes in gastric cancer, and explored its application value in the N staging of gastric cancer with different MSI statuses, so as to provide a more accurate evidence for clinical diagnosis, promote the development of individualized treatment for gastric cancer, and ultimately improve the prognosis of patients.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Diagnostic
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •(a)Patients with gastric adenocarcinoma confirmed by histopathological biopsy and definite microsatellite status determined by immunohistochemistry (IHC);
- •(b)Abdominal dual-phase Quark CT scanning was performed within 2 weeks before surgery;
- •(c)aged ≥ 18 years old
排除标准
- •(a)Combined with other primary tumors;
- •(b) The image quality does not meet the diagnostic criteria;
- •(c)Those who cannot tolerate CT examination.
研究组 & 干预措施
Spectral CT combined with MSI for predicting regional lymph node metastasis in gastric cancer
Medical images and clinical data related to gastric cancer were prospectively collected using a Philips Quark CT scanner, and its diagnostic accuracy and clinical application value in gastric cancer patients with different MSI statuses were evaluated to achieve accurate staging of gastric cancer. Patients diagnosed with gastric cancer at Yunnan Cancer Hospital from August 2025 to December 2026 were consecutively enrolled. After undergoing Philips Quark CT scanning, the N stage of gastric cancer was independently assessed by two radiologists, and statistical analysis was subsequently performed for the final results.
干预措施: o explore the value of spectral CT in the diagnosis and treatment of gastric cancer with different MSI statuses (Diagnostic Test)
结局指标
主要结局
Pathological N stage
时间窗: 1 day
The lymph node status confirmed by surgical pathology was used as the reference standard
次要结局
未报告次要终点