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Restrict volume & vasopressor resuscitation in Pediatric sepsis

Completed
Conditions
Pediatric severe sepsis and need hemodynamic resuscitation.
Resticted volume resuscitation, severe sepsis, pediatric, vasopressor
Registration Number
TCTR20220419007
Lead Sponsor
/A
Brief Summary

Early vasoactive agents did not associate with decreasing time to shock reversal, however the type of inotropic agent might relate to time to shock reversal. Positive fluid overloads and serum albumin level were found to relate with mortality in pediatric with severe septic shock

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
All
Target Recruitment
144
Inclusion Criteria

All pediatric patients aged between one month to 18 years admitted to the PICU with septic shock who received at least one vasoactive agent were enrolled. Those with congenital heart disease with congestive heart failure, chronic kidney disease, and/or signs of volume overload, palliative treatment, and missing data collection were excluded

Exclusion Criteria

Those with congenital heart disease with congestive heart failure, chronic kidney disease, and/or signs of volume overload, palliative treatment, and missing data collection were excluded

Study & Design

Study Type
Observational
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Mortality end of 28 days of PICU admission number of death in PIC
Secondary Outcome Measures
NameTimeMethod
Morbidity End of 28 PICU admission Length of PICU stay
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