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临床试验/NCT03850288
NCT03850288已完成不适用

Inhibitory Control in Eating Disorders (Anorexia Nervosa, Bulimia Nervosa and Binge Eating Disorder)

Hospices Civils de Lyon1 个研究点 分布在 1 个国家目标入组 17 人开始时间: 2019年5月15日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
17
试验地点
1
主要终点
Inhibition processes assessment - the Stroop task, Execution time

研究概览

简要总结

Executive functions are part of the high-level cognitive processes essential to the proper functioning of human cognition. They consist mainly of flexibility, updating and inhibition. Some studies have shown a correlation between executive disorders (impaired executive function) and psychiatric disorders such as obsessive-compulsive disorder or phobias. These executive disorders are related to dysfunctions of the fronto-striatal loops.

In addition, other studies have investigated the link that may exist between eating disorders such as anorexia or bulimia nervosa and executive functioning. Anorexia nervosa, bulimia nervosa and binge eating disorders are eating disorders characterized by a dysfunction in food intake with restriction of food or compulsions as well as strong concerns about the body schema. Concerning the executive functioning, these studies highlight a lack of cognitive flexibility for patients with anorexia nervosa and bulimia nervosa but also dysfunctions depending on the type of pathology (anorexia nervosa or bulimia nervosa). These studies also highlight the beneficial effects of cognitive remediation on people with eating disorders.

However, the investigation of the inhibitory control has not yet been specifically studied. Moreover, since eating disorders are structurally different, a comparison between several pathologies would be interesting to consider.

The aim of this study is to determine if a dysfunction of inhibitory control can be highlighted in people with eating disorders. This study would also allow further researches about cognitive remediation suitable for the specific difficulties encountered in these diseases.

研究设计

研究类型
Observational
观察模型
Other
时间视角
Prospective

入排标准

年龄范围
19 Years 至 40 Years(Adult)
性别
Female
接受健康志愿者

入选标准

  • Woman aged 19 to 40 years old
  • Patient with a BMI between 13 and 40 kg/m2
  • Outpatients of the Refering Center of Eating Disorders ('Hospices Civils de Lyon' in Lyon) suffering of an eating disorder diagnosis (Anorexia Nervosa, Bulimia Nervosa or Binge Eating Disorder)
  • Patient who agrees to participate to the study.

排除标准

  • Patient with psychiatric comorbidity severe (DSM V) and not stable (during the 8 weeks before inclusion)
  • Patient with psychotropic treatment (started or modified during the 8 weeks before inclusion)
  • Major patient protected by a measure of legal protection
  • Patient younger than 19 years old
  • Participation to another study at the same time

结局指标

主要结局

Inhibition processes assessment - the Stroop task, Execution time

时间窗: 1 day

Execution time in the Stroop task

Inhibition processes assessment - the Stroop task, Errors

时间窗: 1 day

Errors in the Stroop task

Inhibition processes assessment - the Go No Go task, Execution time

时间窗: 1 day

Execution time in the Go No Go task.

Inhibition processes assessment - the Go No Go task, Errors

时间窗: 1 day

Errors in the Go No Go task

Inhibition processes assessment - the Go No Go task, Variability of execution time

时间窗: 1 day

Variability of execution time in the Go No Go task

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Sponsor

研究点 (1)

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