NCT03746158已完成不适用
University of Massachusetts Amherst
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 8
- 试验地点
- 2
- 主要终点
- Determine the concentration of curcumin and its metabolites in the human fecal samples.
研究概览
简要总结
The objective of this project is to elucidate the interindividual variations in excretion of curcumin and its metabolites.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 30 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •18-30 year old healthy adults
排除标准
- •Exclusion criteria included those who are <18 or >30 years old, have a BMI of <20 or >29 kg/m2, have a weight change >4.5 kg in the past 3 months, exceed exercise activities of a curcumin level over the past 3 months, have any diseases, especially intestinal disorders, had abnormal liver or kidney function tests. Those who smoke, consume more than two alcoholic drinks per day, use medication affecting gut microbiota profile (e.g., antibiotics and probiotics) in past three months will also be excluded.
- •Additionally, this study excludes menopausal women, those using hormone-based contraceptives, those with abnormal menstrual cycles, and those who are pregnant, lactating or planning to become pregnant.
结局指标
主要结局
Determine the concentration of curcumin and its metabolites in the human fecal samples.
时间窗: 3-4 weeks
Utilize LC-MSMS to identify and quantify the curcumin and its metabolites in the subjects fecal samples.
次要结局
未报告次要终点
研究者
研究点 (2)
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