Reduction of the red cell concentrate use by patient blood management. Changing the pretransfusional hemoglobin trigger by education of transfusion triggers and modification of the transfusion ordering form

• Conditions: D62; D63; Acute posthaemorrhagic anaemia; Anaemia in chronic diseases classified elsewhere

• Registration Number: DRKS00015857
• Lead Sponsor: niversitätsklinikum Greifswald

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Completion: 2018-07-30
• Study Start: 2018-11-08
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 23487

Inclusion Criteria

All patients of the following departments were enrolled: surgical departments (general, trauma, orthopedics, neurosurgery, urology, gynecology and obstetrics, surgical intensive care) and medical departments (gastroenterology, pulmonology, nephrology, cardiology, hemato-oncology, medical intensive care).

Exclusion Criteria

red blood cell exchange transfusion; missing Hb value within 24h before transfusion

Study & Design

• Study Type: observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The primary endpoint was the change of median pretransfusional Hb-values between evaluation periods.

Secondary Outcome Measures

Name	Time	Method
Secondary endpoints were changes in the absolute number of transfused red blood cell concentrates in relation to the number of treated patients, and changes in numbers of red blood cell concentrate-transfusions with a pretransfusional Hb-value of the patient of >10 g/dl.<br>Safety endpoints were the rate of documented in-hospital acute coronary syndrome, all-cause in-hospital mortality, and the length of in-hospital stay.