Prospective Study of Undiagnosed Celiac Disease
- Conditions
- Celiac Disease
- Interventions
- Other: Dietary instruction
- Registration Number
- NCT01317914
- Lead Sponsor
- Mayo Clinic
- Brief Summary
Direct benefits to the participants, who are diagnosed with celiac disease may be substantial and could include lessening or prevention of GI symptoms, correction of biochemical abnormalities and reduction in risk for malignancies or bone disease which are most common in untreated celiac disease. However, the precise benefit is unknown and the motivation for this proposed study. If these individuals have a positive celiac serology test at the present time there is a high likelihood that they may have celiac disease.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 31
- At least 60 years old
- Male and female
Retrospective testing for celiac disease was done on previously stored serum. Contacting specific individuals for inclusion into study
Not provided
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Arm && Interventions
Group Intervention Description Dietary instruction on Gluten Free Diet Dietary instruction -
- Primary Outcome Measures
Name Time Method Understanding the impact of undiagnosed celiac disease and the potential benefits of diagnosis one year To understanding the impact of undiagnosed celiac disease and the potential benefits, detection and treatment may have a substantial impact on the health of these subjects and the large numbers of Americans with undiagnosed celiac disease. The outcome measures we will be looking at are Quality of Life, GI Symptoms including diarrhea, constipation, abdominal pain, Tissue Transglutaminase level improvement after 12 weeks on a gluten free diet, bone density, understanding of a gluten free diet.
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Mayo Clinic in Rochester
🇺🇸Rochester, Minnesota, United States