Cognitive Training for Patients With Schizophrenia

Not Applicable

Completed

• Conditions: Other Primary Psychotic Disorders; Schizophrenia; Schizoaffective Disorder
• Interventions: Behavioral: Cognitive Training

• Registration Number: NCT01521026
• Lead Sponsor: University of California, San Diego

Brief Summary

This research on cognitive training addresses the following questions:

1. Does cognitive training lead to improved cognition, functional abilities, psychiatric symptoms, treatment adherence, or quality of life in patients with psychoses?

2. What are the neurocognitive and non-cognitive factors that predict good outcomes following cognitive rehabilitation? In addition to verbal learning and memory, immediate verbal memory, vigilance, and executive functioning, the cognitive training intervention attempted to improve prospective memory ability (i.e., the ability to remember to do things in the future, such as take medications or attend a doctor's appointment).

Detailed Description

Not available

Study Timeline

• Study Start: 2003-09
• Primary Completion: 2009-08
• Study Completion: 2009-08
• Study First Submitted: 2012-01-22
• Study First Submitted QC: 2012-01-25
• Study First Posted: 2012-01-30
• Results First Submitted: 2013-07-01
• Results First Submitted QC: 2013-11-15
• Results First Posted: 2013-12-11
• Status Verified: 2023-06
• Last Update Submitted: 2023-06-30
• Last Update Posted: 2023-07-05

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 69

Inclusion Criteria

• Primary psychotic disorder (including schizophrenia, schizoaffective disorder, psychotic mood disorder, or psychosis NOS)
• Age 18 or older
• Fluency in English

Exclusion Criteria

• Dementia
• Neurological conditions affecting cognition
• Mental retardation
• Substance use disorder within the past month
• Participation in other intervention trials

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Cognitive Training	Cognitive Training	Cognitive training group

Primary Outcome Measures

Name	Time	Method
UCSD Performance-based Skills Assessment Total Score (Measures Functional Capacity)	3 months	Performance-based measure of functional capacity in five domains: Communication, Finance, Recreation Planning, Transportation, and Household Chores Scale ranges from 0-100. Subscales are summed to yield the total score. Higher scores represent better performance.

Secondary Outcome Measures

Name	Time	Method
Hopkins Verbal Learning Test Percent Retained	3 months	Verbal list learning task with three learning trials and a delay trial. Percent retained refers to the percentage of items recalled at the delay trial, compared to the third learning trial.; Score ranges from 0-100. Higher scores represent better performance.

Trial Locations

Locations (1)

UCSD Outpatient Psychiatric Services; 🇺🇸 San Diego, California, United States