NL-OMON47472
Completed
Not Applicable
Functional neuroimaging and neurophysiological patterns during Zolpidem-induced behavioral improvement in akinetic mutism: a pilot study - Zolpidem in akinetic mutism
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Not specified
- Sponsor
- Academisch Medisch Centrum
- Enrollment
- 2
- Status
- Completed
- Last Updated
- 2 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •\* Diagnosis of AM, caused by non\-progressive neurological injury
- •\* Consistent temporarily restored speech and limb movement following administration of 10 mg Zolpidem
Exclusion Criteria
- •\* Ongoing neurodegenerative disease
- •\* Standard MRI scan exclusion criteria (i.e. pacemaker and other metallic foreign bodies contraindicated for MRI)
- •\* Motor agitation interfering with MRI, EEG or MEG
- •\* Anatomical deformities that prevent the subject from undergoing MEG registration in supine position (i.e. thoracic kyphosis)
Outcomes
Primary Outcomes
Not specified
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