NCT01059331
Completed
Phase 4
Perioperative Administration of Pregabalin in Laparoscopic Living Donor Nephrectomy (L-LDN) - an Adjuvance to Peroral Analgetic Treatment - a Randomized Controlled Study
Oslo University Hospital1 site in 1 country80 target enrollmentFebruary 2010
Overview
- Phase
- Phase 4
- Intervention
- Pregabalin
- Conditions
- Living Donors
- Sponsor
- Oslo University Hospital
- Enrollment
- 80
- Locations
- 1
- Primary Endpoint
- Opioid consumption in milligrams Pain Score given as Numeric Rating Scale (NRS)
- Status
- Completed
- Last Updated
- 12 years ago
Overview
Brief Summary
The aim of the study is to investigate if perioperative administration of pregabalin vil reduce postoperative pain and the postoperative need for intravenous opioids compared with todays standard treatment which consist of paracetamol, corticoids and ketobemidone.
In addition potential sideeffects as sedation and effect on cognitive function will be recorded.
Investigators
Marianne Myhre
cand.med.
Oslo University Hospital
Eligibility Criteria
Inclusion Criteria
- •\>18, \< 75 years
- •healthy patients accepted for laparoscopic living donor nephrectomy
Exclusion Criteria
- •not familiar to the Norwegian language (spoken and written)
- •allergic to one or more of the medication given in the study
Arms & Interventions
Pregabalin
Intervention: Pregabalin
Sugar pill
Intervention: Sugar pill
Outcomes
Primary Outcomes
Opioid consumption in milligrams Pain Score given as Numeric Rating Scale (NRS)
Time Frame: Daily troughout the hospital stay, approx. 6 days
Secondary Outcomes
- Sedation and cognitive function(Daily troughout the hospital stay, approx. 6 days)
Study Sites (1)
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