Postoperative Analgesia After Laparoscopic Living Donor Nephrectomy

Phase 4

Completed

• Conditions: Living Donors
• Interventions: Drug: Pregabalin; Drug: Sugar pill

• Registration Number: NCT01059331
• Lead Sponsor: Oslo University Hospital

Brief Summary

The aim of the study is to investigate if perioperative administration of pregabalin vil reduce postoperative pain and the postoperative need for intravenous opioids compared with todays standard treatment which consist of paracetamol, corticoids and ketobemidone.

In addition potential sideeffects as sedation and effect on cognitive function will be recorded.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2010-01-28
• Study First Submitted QC: 2010-01-28
• Study First Posted: 2010-01-29
• Study Start: 2010-02
• Primary Completion: 2011-10
• Study Completion: 2012-12
• Status Verified: 2014-03
• Last Update Submitted: 2014-03-20
• Last Update Posted: 2014-03-21

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 80

Inclusion Criteria

• >18, < 75 years
• healthy patients accepted for laparoscopic living donor nephrectomy

Exclusion Criteria

• not familiar to the Norwegian language (spoken and written)
• allergic to one or more of the medication given in the study

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Pregabalin	Pregabalin	-
Sugar pill	Sugar pill	-

Primary Outcome Measures

Name	Time	Method
Opioid consumption in milligrams Pain Score given as Numeric Rating Scale (NRS)	Daily troughout the hospital stay, approx. 6 days

Secondary Outcome Measures

Name	Time	Method
Sedation and cognitive function	Daily troughout the hospital stay, approx. 6 days

Trial Locations

Locations (1)

Oslo Universitetssykehus, Rikshospitalet; 🇳🇴 Oslo, Norway