Image quality on the MR-HIFU breast system.
- Conditions
- Our final goal is to treat patients with breast cancer using the MR-HIFU breast system. Before we can do this, we have to go through several steps. The first step is to assess the quality of images acquired on the MR-HIFU system.
- Registration Number
- NL-OMON20705
- Lead Sponsor
- niversity Medical Center Utrecht, Department of Radiology
- Brief Summary
/A
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- Not specified
- Target Recruitment
- 30
Inclusion Criteria
Inclusion criteria for volunteers:
1. Women;
Exclusion Criteria
Exclusion criteria for volunteers and patients with fibroadenomas:
1. Contra-indications for MRI scanning according to the guidelines of the hospital;
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1. Image quality --> assessed by a score based on delineation of anatomical structures contrasts, SNR and artefacts of both MRI scans;<br /><br>2. Lesion descriptors of the BI-RADS lexicon in patients with a fibroadenoma --> described by shape and margin of the lesion and other findings on the MRI scans (e.g. edema, lymphadenopathy, skin thickening).
- Secondary Outcome Measures
Name Time Method 1. Geometric deformation in breasts with different sizes --> assessed by overlaying the two MRI scans and assess whether there is deformation and assess the variety of deformation in breasts;<br /><br>2. Size of fibroadenoma --> assessed by scoring the maximum diameter of the fibroadenoma in 3 orthogonal planes (MaxTrans, MaxSag, MaxCor) on both MRI scans;<br /><br>3. Relative position of the fibroadenoma --> assessed by measuring the shortest distance from the fibroadenoma to the musculus pectoralis, the chest wall and the skin in 3 orthogonal planes (MaxTrans, MaxSag, MaxCor) on both MRI scans.