CT Iterative ReConstruction for Low-dose cardiopulmonary, abdominal and musculoskeletal Evaluation: image quality and diagnosis of coronary calcium, pulmonary nodules, urinary stones and the ankle joint
- Conditions
- Patiënten die doorverwezen worden voor CT-hart (indicatie: hart en vaatziekten), CT-thorax (indicatie: follow-up voor longnodules), CT-abdomen (indicatie: follow-up voor nierstenen) en CT-enkel.Not applicable
- Registration Number
- NL-OMON41431
- Lead Sponsor
- niversitair Medisch Centrum Utrecht
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 120
Cardiac CT:
* * 50 years old
* The indication for the CT-scan is suspected cardiovascular disease
* Written informed consent;Chest CT:
* * 50 years old
* Patients with one or more known pulmonary nodules
* The indication for the CT-scan is follow-up of one or more pulmonary nodules
* Written informed consent;Abdominal CT:
* * 40 years old
* The indication for the CT-scan is follow-up of urinary stones
* Written informed consent;Ankle CT:
* * 18 years old
* The indication for the CT-scan is suspected orthopaedic abnormalities
* Written informed consent
* Patient not meeting the inclusion criteria
* Previous participation in the study
* Pregnant women
* Concomitant participation in a study in which the patient is exposed to X-rays
Study & Design
- Study Type
- Observational invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>The main study parameters are normal-dose CT and low-dose CT. The main<br /><br>endpoints are the subjective and objective image quality at different dose<br /><br>reduction levels for both standard and iterative reconstruction.</p><br>
- Secondary Outcome Measures
Name Time Method <p>Secondary endpoints are coronary calcifications (cardiac CT), pulmonary nodule<br /><br>volume (chest CT) and detectability and size of urinary concrements (abdominal<br /><br>CT).</p><br>