Implementing dynamic cardiac CT in a standardized diagnostic work-up for native valve infective endocarditis.

Recruiting

• Conditions: Endocarditis. Heart valve infection; 10014662; 10004018

• Registration Number: NL-OMON51466
• Lead Sponsor: Radboud Universitair Medisch Centrum

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 6 May 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: Not specified
• Target Recruitment: 40

Inclusion Criteria

-Patients aged > 18 years old hospitalized at the Radboudumc with a clinical
suspicion of infective endocarditis
-Positive blood cultures
-Clinical indication for TEE, according to current guideline recommendations

Exclusion Criteria

-Pregnancy or breastfeeding
-Prosthetic heart valve
-Cardiovascular implantable electronic device
-Body mass index > 35 kg/m2
-Glomerular filtration rate < 30 mL/min/1.73 m2
-Previous allergic reaction to iodine contrast dye

Study & Design

• Study Type: Observational non invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The diagnostic accuracy of dynamic cardiac CT in additon to and in comparison<br /><br>with TEE.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>-Cost effectiveness analysis of dynamic cardiac CT in addition to and in<br /><br>comparison with TEE.<br /><br>-Retrospectively allocated treatment strategy based dynamic cardiac CT in<br /><br>addition to and in comparison with TEE.<br /><br>-Interobserver variability of dynamic cardiac CT regarding the diagnosis NVE. </p><br>