The Effect of Peroperative Fluid Management Strategy on Postoperative Renal Functions in Major Gyneco-oncological Surgeries
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 180
- 试验地点
- 2
- 主要终点
- Evaluation of acute kidney injury
研究概览
简要总结
The aim of this study is to evaluate the effect of perioperative fluid management on postoperative kidney damage in gynecological cancer surgeries.
The main question[s] it aims to answer are:
Does fluid management applied with different hemodynamic monitoring methods affect the risk of postoperative AKI? In our clinic, three different fluid management strategies are applied depending on the anesthetist experience. Acute kidney injury will be evaluated according to the postoperative AKIN classification of conventional fluid therapy and targeted fluid therapy with noninvasive or minimally invasive monitoring.
详细描述
Our study was designed as a retrospective study. The files of patients over the age of 18 who underwent open abdominal surgery due to ASAII and III gynecological malignancy will be examined retrospectively. Patients who cannot be monitored peroperatively and who undergo HIPEC will be excluded from the study. Patients will be divided into 3 groups according to the fluid management strategy and the hemodynamic monitoring used: Group 1: patients receiving conventional fluid therapy; Group 2: patients receiving targeted fluid therapy with noninvasive monitoring; Group 3: patients receiving targeted fluid therapy with minimally invasive monitoring.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 主要目的
- Health Services Research
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •>18 years
- •ASA II-III
- •Those with normal renal function
排除标准
- •Patients in renal insufficiency
- •Patients with perioperative renal, ureter & bladder invasion
- •Patients in whom perioperative urine monitoring cannot be performed
- •Patients undergoing HIPEC
- •Patients with missing data
结局指标
主要结局
Evaluation of acute kidney injury
时间窗: Change from preoperative to postoperative day 1(POD1)creatinine values(mg/dl)
Our primary aim was to evaluate the postoperative day(POD1 ) creatinine values(mg/dl)
次要结局
- Peroperative fluid amounts(during the operation period)
研究者
Duygu Akyol
Principal investigator
Bakirkoy Dr. Sadi Konuk Research and Training Hospital