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Differential severity of COVID-19 outcomes between Indians in India and the UK

Not Applicable
Registration Number
CTRI/2021/07/034623
Lead Sponsor
Indian Institute of Public Health Bangalore Public Health Foundation of India
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
ot Yet Recruiting
Sex
Not specified
Target Recruitment
0
Inclusion Criteria

1.Participants from the MAASTHI and APCAPS cohort.

2.COVID-19 positive diagnosed patients willing and able to give informed consent.

3.In case of death, next of kin willing to participate

Exclusion Criteria

1. Participants below 18 years

2. No informed consent

Study & Design

Study Type
Observational
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Differences in severity rates of COVID-19 between Indian populations in India compared to UK: <br/ ><br>1. in age-sex composition and epidemiological curve <br/ ><br>2. by burden of obesity, cardio-metabolic conditions or respiratory conditions <br/ ><br>3. by cross-immunity acquired from exposure to other coronaviruses or immunity acquired from tuberculosis, BCG vaccination, malaria <br/ ><br>4. Determine biological mechanisms linking severe COVID-19 to obesity, cardio-metabolic disease, respiratory conditions, immunity? <br/ ><br>Timepoint: 1.Every two months <br/ ><br>2. Post hospitalization or death <br/ ><br>
Secondary Outcome Measures
NameTimeMethod
Differences in severity rates of COVID-19 between Indian populations in India compared to UK: <br/ ><br>1. in age-sex composition and epidemiological curve <br/ ><br>2. by burden of obesity, cardio-metabolic conditions or respiratory conditions <br/ ><br>3. by cross-immunity acquired from exposure to other coronaviruses or immunity acquired from tuberculosis, BCG vaccination, malaria <br/ ><br>4. Determine biological mechanisms linking severe COVID-19 to obesity, cardio-metabolic disease, respiratory conditions, immunity? <br/ ><br>Timepoint: 1.Every two months <br/ ><br>2. Post hospitalization or death
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