Exercise Intervention - and Impact on Hospitalization

Not Applicable

Terminated

• Conditions: Sarcopenia; Debility Due to Disease
• Interventions: Behavioral: exercise; Other: placebo

• Registration Number: NCT03106220
• Lead Sponsor: Mayo Clinic

Brief Summary

Skeletal muscle abnormalities (sarcopenia) and frailty are common complications seen in patients with end-stage liver disease. The presence of these complications portends poor prognosis. The purpose of this study is to assess the impact of a formal home based video strengthening program (REST) on sarcopenia and frailty. We also want to assess the impact of this exercise program on complication rates, hospitalization, on quality of life (QOL) and on survival.

Detailed Description

Not available

Study Timeline

• Study Start: 2017-03-01
• Study First Submitted: 2017-03-30
• Study First Submitted QC: 2017-04-04
• Study First Posted: 2017-04-10
• Primary Completion: 2021-01-14
• Study Completion: 2021-01-14
• Status Verified: 2021-02
• Last Update Submitted: 2021-03-03
• Last Update Posted: 2021-03-05

Recruitment & Eligibility

• Status: TERMINATED
• Sex: All
• Target Recruitment: 19

Inclusion Criteria

Not provided

Exclusion Criteria

Not provided

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Arm && Interventions

Group	Intervention	Description
home exercise	exercise	participate in home exercise program
standard care	placebo	encouraged to join physical therapy and walking goals

Primary Outcome Measures

Name	Time	Method
6MWT	3 months	6 minute walk
hand grip	3 months	hand grip

Trial Locations

Locations (3)

Mayo Clinic in Arizona; 🇺🇸 Scottsdale, Arizona, United States

Mayo Clinic in Florida; 🇺🇸 Jacksonville, Florida, United States

Mayo Clinic in Rochester; 🇺🇸 Rochester, Minnesota, United States