跳至主要内容
临床试验/CTRI/2025/08/092894
CTRI/2025/08/092894尚未招募不适用

A Clinical Study to evaluate the effect of Durvadi Ghrita and Jatyadi Ghrita with manual anal dilatation in Parikartika W.S.R to Fissure-in-ano

Dr Sarika Gupta1 个研究点 分布在 1 个国家目标入组 120 人开始时间: 2025年8月22日最近更新:

试验速览

阶段
不适用
状态
尚未招募
发起方
入组人数
120
试验地点
1
主要终点
Does Durvadi Ghrita show more effect in comparison to Jatyadi Ghrita in the management of Parikartika (Fissure in ano)

研究概览

简要总结

Anal fissure is one of the major causes for pain of anal region. An anal fissure

is a longitudinal tear in the skin of the anal canal distal to the dentate line. The disease

fissure in ano can be compared with Parikartika according to Ayurveda. The disease

Parikartika has been described in Charaka Samhita sidhisthana chapter 7 in Niruhabasti

Vyapd.

In the present study, an effort is made to derive a standard, cost effective and

easily accessible treatment for fissure-in-ano from classical resources. The efficacy of Durvadi Ghrita

and Jatyadi Ghrita in the management of Parikartika is evaluated in this study.

120 patients are taken in this study and randomly divided into 2 groups. (Each group having 60

patients)

Group 1 - 60 Patients receive local application of Durvadi Ghrita and

Group 2 - 60 Patients receive local application of Jatyadi Ghrita along with manual anal dilatation.

Durvadi Ghrita and Jatyadi Ghrita are the non-invasive, easy and cost-effective without any adverse

effects management for fissure-in-ano and also better alternatives in place of modern techniques,

especially in acute fissure-in-ano.

• PROCEDURE: - Per rectal application of Durvadi Ghrita and Jatyadi Ghrita pichu

(3ml each) daily along with manual anal dilatation.

• DURATION: - 21 days or till symptoms relief.

• SITZ BATH: - Every 6hrly and after defecation with lukewarm water.

• FOLLOW UP: - after completion of study duration follow up for 7th, 14th, 21st days.

• STUDY DURATION: - 42 days.

研究设计

研究类型
Interventional
分配方式
Randomized
盲法
None

入排标准

年龄范围
18.00 Year(s) 至 60.00 Year(s)(—)
性别
All

入选标准

  • Patient between the age of 18 to 60 years will be taken irrespective of sex, religion, occupation, and economic status.
  • Patients fulfilling the above-mentioned diagnostic criteria.
  • Patients having classical features of acute fissure-in-ano like Kartanvat vedana, Daha, Vibandha, Rakta-srva and kandu will be included.

排除标准

  • Fissure secondary to ulcerative colitis, tuberculosis, syphilis, Crohn’s disease and other systemic diseases pertaining to colorectum will be excluded from the study.
  • Patient with Ca rectum, Ca anus, Fistula in ano and hemorrhoids will be excluded.
  • Patient for not willing to undergo the procedure.
  • Portal hypertension.
  • Anal deformity.
  • Hypertension within the range of 140/
  • Diabetes Mellitus- specially HbA1c cases.

结局指标

主要结局

Does Durvadi Ghrita show more effect in comparison to Jatyadi Ghrita in the management of Parikartika (Fissure in ano)

时间窗: 21 days

次要结局

  • Role of Durvadi Ghrita with manual anal dilatation in the treatment of Parikartika.(Role of Jatyadi Ghrita with manual anal dilatation in the treatment of Parikartika.)

研究者

发起方
Dr Sarika Gupta
申办方类型
Other [self]
责任方
Principal Investigator
主要研究者

Dr Anita Patel

Shree Swaminarayan University, Kalol

研究点 (1)

Loading locations...

相似试验