comparison of three different types of injections on the chest for pain relief in breast surgeries

Phase 2/3

Completed

• Conditions: Malignant neoplasm of breast,

• Registration Number: CTRI/2016/06/007047
• Lead Sponsor: All India Institute of Medical Sciences

Brief Summary

Breast surgeries are associated with significant post operative pain which may progress to chronic pain. Regional techniques reduce the postoperative acute pain which results in reduced morbidity and decreased consumption of opioids. Paravertebral block is commonly used for breast surgeries. However it is associated with many complications.

Two new ultrasound guided interfascial plane blocks-PECS II and serratus plane block have been recently described which are more selective, have less complications and may provide better analgesia.

There are no studies comparing these blocks for breast surgery. Also, evaluating the area of sensory blockade in large number of patients will help in describing the extent of blockade more accurately and their use may extend beyond breast surgeries. This study is designed to study about these new techniques under ultrasound guidance to ensure maximum safety and find their analgesic efficacy.

Therefore, we hypothesize that

·         PECS II and serratus plane block will provide better analgesia than paravertebral block for breast surgeries with lesser side effects.

·         Serratus plane block will provide better sensory blockade and analgesia than PECS II block.

Detailed Description

Not available

Study Timeline

• Study Start: 2016-01-07
• Study Completion: 2017-09-28
• Last Update Posted: 2019-05-29

Recruitment & Eligibility

• Status: Completed
• Sex: Female
• Target Recruitment: 45

Inclusion Criteria

ASA 1 and 2 undergoing elective mastectomy surgeries.

Exclusion Criteria

coagulopathy BMI >35kg/m2 pregnancy mental retardation chest wall deformity.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
1.Find out the spread of local anesthetic radiographically and co-relate it with the sensory blockade produced.	1.radiographic spread seen immediately after injecting the drug. sensory block seen 15-30 minutes after injecting the drug | 2.total fentalyl consumption seen at 24 hours after the surgery
2.To compare the post operative 24 hour fentanyl consumption.	1.radiographic spread seen immediately after injecting the drug. sensory block seen 15-30 minutes after injecting the drug | 2.total fentalyl consumption seen at 24 hours after the surgery

Secondary Outcome Measures

Name	Time	Method
•Onset of sensory blockade	•Intra-operative opioid requirement

Trial Locations

Locations (1)

All India Institute of Medical Sciences, New delhi; 🇮🇳 South, DELHI, India

All India Institute of Medical Sciences, New delhi

🇮🇳South, DELHI, India

Dr Dhruv Jain

Principal investigator

7042129423

dhruvjn@gmail.com