Comparison of two pain reducing techniques after breast cancer surgery.

Completed

Conditions: Patients with breast cancer

Registration Number: CTRI/2018/04/012915

Lead Sponsor: AIIMS

Brief Summary: Acute postoperative pain due to insufficient pain control is a major risk factor for development of chronic pain after breast surgery. Regional anaesthesia is considered protective for cancer recurrence by its direct and indirect anti proliferative effects. Use of these techniques is associated with better pain control , decreased opioid consumption and their side effects. Paravertebral block is a established regional anaesthesia and analgesia technique for breast cancer surgeries.However erector spinae plane block is a novel interfacial block technique which can be a viable alternative to paravertebral block due to its fast , easy and safe execution . There are numerous studies on paravertebral block but there is a very limited literature on erector spinae plane block in breast surgeries and there is no study comparing paravertebral block with erector spinae plane block in breast surgeries.Thus we are performing this randomized controlled trial to compare the efficacy of paravertebral block with erector spinae plane block in breast surgeries in total 80 patients ( 40 in each group). In Group P , ultrasound guided paravertebral block will be given at T4 level with 20 ml of 0.5 % Ropivacaine and in Group E , ultrasound guided erector spinae plane block will be given at T5 level with 20 ml of 0.5 % Ropivacaine. After giving the block , GA will be given.Any block related complications will be noted. In postoperative period the efficacy of both the blocks will be compared in terms of duration of postoperative analgesia (time to first rescue analgesic ) , total number of rescue analgesics required and patient satisfaction .

Detailed Description: Not available

Recruitment & Eligibility

Status: Completed

Sex: Female

Target Recruitment: 80

Inclusion Criteria

1.ASA I and II 2.Patients posted for MRM 3.Patients giving written informed consent to participate in the study.

Exclusion Criteria

1.Patient refusal 2.Age <18 or > 70 years 3.Patients with BMI > 35kg/m2 4.Patient with infection at the site of injection 5.Coagulopathy 6.Spine deformity 7.Drug addicts or history of opioid dependence 8.Patients with history of allergy to opioids or local anaesthetics.

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To measure the duration of post-operative analgesia (that is, time to first analgesic request from the time of giving block ).	Pain assessment would be done in immediate post (0 min), 30 min, 1 hr , 2hr , 6hr, 12 and 24 hr.

Secondary Outcome Measures

Name	Time	Method
1) Total rescue analgesic requirement in postoperative period.	2) To evaluate patient satisfaction in postoperative period.

Trial Locations

Locations (1): AIIMS , New Delhi
🇮🇳
South, DELHI, India
AIIMS , New Delhi
🇮🇳South, DELHI, India
Dr Shilpi Agarwal
Principal investigator
9650797105
drshilpi87@gmail.com